is benzoic acid soluble in hexane

Benzoic acid can be purified by recrystallization from water because of its high solubility in hot water and poor solubility in cold water. Malonic Typical(benzoic acid, be insoluble in hexane) 0.54. Its presence in food products or food packaging is banned in the United States. It is insoluble in 2.0 M HCl . Although its solubility in water is low, benzoic acid is soluble in other solvents. In a newborn infant with an initial episode of hyperammonemia, arginine should be used until the diagnosis is established (seeTable 103.5). An increase in acid solubility was observed with temperature in all mixtures. What is the definition of marginal in economics? Disclaimer: ECHEMI reserves the right of final explanation and revision for all the information. Benzophenone is a different chemical than benzophenone-3 (also called oxybenzone) and benzophenone-4 (also called sulisobenzone). Service will be provided by either shears or clippers, upon customer request and finished with a straight razor for a detailed finish. In an alkaline environment, benzoic acid is split into ions and thus loses its preserving activity. Hence BF3 is a weaker Lewis acid than BCl3 . The name is derived from gum benzoin, which was for a long time its only source. Salts are ionic compounds and they are readily soluble in 103.12). Benzoic acid is rapidly metabolized and excreted as hippuric acid. Both these compounds are composed of a substituted benzene ring. Benzoic acid is not soluble in water whereas its conjugate base is. During use it is mixed dry in bulk liquids where it promptly dissolves. There is a magazine called vai. Robert M. Kliegman MD, in Nelson Textbook of Pediatrics, 2020. As the solvent becomes more and more basic, the benzoic acid begins to dissolve, until it is completely in solution. Chemistry also involves understanding the properties and interactions of individual atoms and molecules for use in larger-scale applications. . Under California Proposition 65, there is no safe harbor for benzophenone in any personal care products, including sunscreens, anti-aging creams, and moisturizers. Suryanarayana Polaka, Rakesh Kumar Tekade, in Pharmacokinetics and Toxicokinetic Considerations, 2022. Study with other students and unlock Numerade solutions for free. 103.12). Benzoic acid or benzene-carbonic-acid is a monobasic aromatic acid, moderately strong, white crystalline powder, The solubility of benzoic acid has been determined in, In this Fischer esterification reaction, benzoic acid (a carboxylic acid) is esterified with methanol (an alcohol) in the presence of sulfuric acid (an acid catalyst) to. When the reaction tubes containing the benzoic acid and 0.25 ml of the solvent, were set to boiling, there was complete dissolution in the tubes containing water and. Account for the different properties of ionic and covalent compounds by referring to the forces of attraction between ions or molecules. between countries, or between the East and West Coast of the US) without a change in the packaging. Malonic acid, a polar molecule that is also able to ionize, was found to be soluble in water and methyl alcohol but insoluble in hexane. If the ACD is superimposed upon another dermatosis (e.g. Benzoic acid was also insoluble in 1.0 M HCl. Application. Benzoic acid can sometimes be found in food stores as food preservative, though most of the time it's just plain old sodium benzoate, as the latter is more soluble in water. If it did, it the solution would have some electrical conductivity (that is how you can check if a molecule is dissociating in a The International Dairy Federation has adopted an LC method as a standard method for the determination of the benzoic acid and sorbic acid content of milk, dried milk, yogurt, and other fermented milks (IDF standard 139: 1987). Answers: Benzoic acid is more soluble in diethyl ether than water. Another valuable therapeutic adjunct is IV infusion ofarginine, which is effective in all patients (except those with arginase deficiency). Salicylic acid helps the body shed rough or dead skin cells. The formation of the hydrogen bonding is shown. Treatment of ACD primarily involves identification of the causative allergens. benzoic acid cannot dissociate in benzene. If it did, it the solution would have some electrical conductivity (that is how you can check if a molecule is dissociating in a solvent, by measuring their electrical conductivity). So benzene must be overcoming the intermolecular attraction among benzoic acid "molecule". Benzophenone can also cause 'photoallergy'. Because the kidneys clear ammonia poorly, its removal from the body must be expedited by formation of compounds with a high renal clearance. With this CAMP-generated list, the patients can then purchase products that lack the ingredients to which they are allergic. Finally biphenyl, a very nonpolar molecule, was found to be soluble in hexane but insoluble in water and methyl alcohol. The human health effects from skin exposure to low levels of BP-3 are unknown. Also, in the medical field, it is a major contributor. Ringworm and athlete's foot are treated with the chemical. Round-Up The entire narrative began with the question, "why does benzoic acid not dissolve in water?" Decarboxylation of benzoic acid or its salts will yield benzene . Benzoic acid is a colorless solid, poorly soluble in water, but more soluble in organic solvents. Benzoic acid can sometimes be found in food stores as food preservative, though most of the time it's just plain old sodium benzoate, as the latter is more soluble in water. This is your one-stop encyclopedia that has numerous frequently asked questions answered. Also to know is, is benzoic acid soluble in water at room temperature? How is benzophenone broken down in the environment? The acids are then extracted from the ether solution into aqueous alkali, and after acidification they are re-extracted into dichloromethane. In patients with citrullinemia, 1 mole of arginine reacts with 1 mole of ammonia (as carbamoyl phosphate) to form citrulline. If a truck transporting ethanol is involved in a fire, choose the best way to mitigate, Benzene, toluene, and xylene (commonly known as BTX) are the three most commonly encountered aromatic hydrocarbons. , or can extract the benzoic acid with ether. Why is benzophenone insoluble in methyl alcohol? Phenol is soluble in water to some extent. Benzoic acid dissolves better in ether than in water, but sodium benzoate dissolves better in water than in ether. An alternative method of isolating benzoic acid from food involves the use of steam distillation and TLC separation. However the large part of phenol molecule is phenyl group that is non polar and hence its solubility if limited in water. ScienceChemistryOrganic Chemistry Answer Step #1 of 2 ability to dissolve solid, liquid and gases in solvent is known as Solubilty. produces a water-soluble, pleasant-smelling white powder that is used for flavorings and perfume In contrast, in the formation of a complex with a weak base such as CO, the BX3 is barely distorted from planarity and so the acidity of BF3 is greater than that of BCl3 because the charge on boron is greater in BF3 than BCl3. It can also cause skin irritation and allergic contact dermatitis, which presents with a red, itchy, scaly rash," he said. Explain why. 4. Administration of arginine or citrulline is contraindicated in patients witharginase deficiency, a rare condition in which the usual presenting clinical picture is spastic diplegia rather than hyperammonemia. Clinical outcome depends mainly on the severity and the duration of hyperammonemia. Anjan Nan, in Side Effects of Drugs Annual, 2016. The structure of C 600 H is the same as before. The solubility of benzoic acid has been determined in ethanol, toluene, heptane, cyclohexane, pentane, and chloroform and in binary mixtures of ethanol + heptane and ethanol + toluene, in the temperature range of (278.15 to 323.15) K. This is a question our experts keep getting from time to time. Set up the reflux and start mixture to reflux for 3 to 4 hours until oily toluene disappears. In contrast, in the formation of a complex with a weak base such as CO, the BX3 is barely distorted from planarity and so the acidity of BF3 is greater than that of BCl3 because the charge on boron is greater in BF3 than BCl3. At room temperature, benzoic acid was completely dissolved when 0.25 ml of the, solvents methanol and toluene were added and stirred well, while it was insoluble when. The main difference between phenol and benzoic acid is that, Abstract: Benzoic Acid was recrystallized with a 41% recovery using. Therefore, the correct answer is benzoic acid is converted to benzaldehyde by chlorination and then followed by the reduction reaction which is a named reduction reaction. Typical(benzoic acid, be soluble in nahco3) Typical and Remarkable implies Salient. So due to this intermolecular hydrogen bonding benzophenone is soluble in methyl alcohol. -During the reaction benzonitrile and phenyl magnesium bromide should be taken in equimolecular proportion. These sample preparation techniques are used in AOAC method 967.15 prior to the determination of benzoic acid by UV absorption. but not in water. Benzophenone is a mutagen, carcinogen, and endocrine disruptor. a. Polynuclear aromatic. Benzoic acid action limits bacterial growth to a larger extent. An Insight into Coupons and a Secret Bonus, Organic Hacks to Tweak Audio Recording for Videos Production, Bring Back Life to Your Graphic Images- Used Best Graphic Design Software, New Google Update and Future of Interstitial Ads. Once allergens are positively identified, the patient should be given written information on all of these chemicals. Benzophenone, which is largely nonpolar, but possesses a polar carbonyl group, was found to be partially soluble in methyl alcohol and hexane but insoluble in water. Our experts have done a research to get accurate and detailed answers for you. WebA: Given : Methyl benzoate is insoluble in water but soluble in concentrated H2SO4. If you want to test the overall solubility of the substance, you are better off using other substances such as ethyl acetate or hexane. In the laboratory it can be prepared by the dehydration of benzamide or by the Rosenmundvon Braun reaction using cuprous cyanide or NaCN/DMSO and bromobenzene. Except where otherwise noted, data are given for materials in their, http://www.sciencemadness.org/smwiki/index.php?title=Benzoic_acid&oldid=14063, Articles containing unverified chemical infoboxes, GNU Free Documentation License 1.3 or later, 249.2C (480.6F; 522.3K) (decomposes at 370 C). What is the largest housing project in America? To treat fungal diseases, medications containing benzoic acid formulations are employed. Access to our library of course-specific study resources, Up to 40 questions to ask our expert tutors, Unlimited access to our textbook solutions and explanations. In photochemistry benzophenone is commonly used as a? Yes, it is used in the food and chemical industries majorly. Answer Wiki. Apparently, they can help preserve the hair dye you use and may protect the hair cuticle from ultraviolet damage. Therefore the stronger Lewis acid among the given is Fe3+. BOILING POINT: 480 F (249 C) MELTING POINT: 252 F (122 C) SPECIFIC GRAVITY: 1.2659 @ 15 C VAPOR PRESSURE: 1 mmHg @ 205 F PH: 2.8 (satd solution) SOLUBILITY IN WATER: 2.9% @ 20 C VAPOR DENSITY: 4.2 SOLVENT SOLUBILITY: What does benzoic acid dissolve in? The primary reason benzoic acid dissolves only slightly or poorly in cold water is that, because of polar carboxylic group, the bulk amount of the benzoic acid molecule is non-polar. Beyond that, water molecules can stabilize the formation of the benozate ion. This is a question our experts keep getting from time to time. Aluminium chlorofluoride, ACF (AlClxF3x), and high surface aluminium fluoride, HS-AlF3, are the strongest solid Lewis acids described so far. In patients with CPS1 or OTC deficiencies arginine administration is indicated because this amino acid is not produced in sufficient amounts to enable endogenous protein synthesis. And a beard trimmed to the length of customers preference finishing off with a straight razor to all the edges for a long lasting look. Benzophenone, which is largely nonpolar, but possesses a polar carbonyl group, was found to be partially soluble in methyl alcohol and hexane but insoluble in water. This page was last modified on 2 September 2021, at 15:29. The Contact Allergen Management Program (CAMP) is another feature of the website (available to members of the society): this allows the user to input the known allergens and the database assembles a list of products free of the allergens entered. We are a Barber Shop located in Carrollwood Village Fl, we provide a great environment for our clients. So, feel free to use this information and benefit from expert answers to the questions you are interested in! When benzene is treated with bezoyl chloride in the presence of anhydrous aluminium chloride benzophenone is formed. Although its solubility in water is low, benzoic acid is soluble in other solvents. So benzoic acid would be in the organic layer. Get the detailed answer: 1. Explain why ethyl acetate, a non-polar (very low polarity)solvent, can be used to separate the nonpolar fats from the caseinprotein. Benzoic acid and its salts may be determined by titration with sodium hydroxide after extraction of the benzoic acid from an aqueous food suspension into chloroform, and evaporation of the chloroform and any acetic acid present (AOAC method 963.19). By continuing you agree to the use of cookies. Thin Layer Chromotography: If you had a mixture of naphthalene and phenol what compound would you expect to have a higher RF value? Ion chromatography has also been described for the analysis of benzoic acid and sorbic acid, together with artificial sweeteners, caffeine, theobromine, and theophylline. Among foods commonly preserved with the acid are soft drinks, fruit juices, fermented vegetables, and high-sugared foods. Your email address will not be published. Members are provided with comprehensive ways to promote their products. Reasons for Poor Solubility in Cold Water The carboxylic acids generally are soluble in such organic solvents as ethanol, toluene, and diethyl ether We can prepare benzoic acid from toluene by laboratory process. However it does not include massless particles such as photons, or other energy phenomena or waves such as light or sound. How will you prepare benzoic acid from toluene? Benzoic acid is mainly consumed in the production of phenol by oxidative decarboxylation at 300400 C: Therefore the stronger Lewis acid among the given is Fe3+. 0.12. Aspirin (acetylsalicylic acid) is an aromatic compound containing both a carboxylic acid functional group and an ester functional group. 103.12). Answer: Benzonitrile can be converted into acetophenone (benzophenone) by using Grignard's reagent. Abstract: Benzoic Acid was recrystallized with a 41% recovery using 95% ethanol and water as the mixed-solvent. Benzophenone sensitivity produces classic allergic contact dermatitis as well as photocontact dermatitis. Explain why aspirin is more soluble in ethanol than in water. Firstly, ethanoyl chloride reacts with aluminium chloride and produces an electrophile. After adding another 0.25 ml of hexane to the partially dissolved tube and boiling. Propose a reason why the seperation of the components resulted Hence BF3 is a weaker Lewis acid than BCl3 . Are your sideburns and neck line looking funny but the hair cut still looks good come and get a Outline of the hairline performed with an electrical trimmer, as well as a straight-razor shave to the back of the neck and sideburn.That will add more time until your next haircut. We know that C six C O, which is a polar compound and water is also a polar molecule, is the reason why Ben's weak acid is dissolved in water. If you continue to use this site we will assume that you are happy with it. Jeffrey M. Perlman, Joseph J. Volpe, in Volpe's Neurology of the Newborn (Sixth Edition), 2018. Answers:Benzoic acid is insoluble in water and soluble in 2.0 M NaOH. Our team has collected thousands of questions that people keep asking in forums, blogs and in Google questions. Xylene Toluene Benzene, Also , how do you find the mixture that forms a binary azeotrope?. Malonic acid, a polar molecule that is also able to ionize, was found to be soluble in water and methyl alcohol but insoluble in hexane. Benzoic acid was also insoluble in 1.0 M HCl. Benzophenone can migrate to food from packaging printed with UV-cured inks, either by direct contact or by benzophenone vapors. However, both substances are known to cause non-immunological contact reactions (pseudoallergy). It is not considered as a toxic compound. Why is benzoic acid insoluble in water? (21) have reported the solubility of benzoic acid in (acetic acid + water) for the higher mass fraction of acetic acid ranges from 0.8 to 1.0. Once the allergens have been identified, the physician should try to clear the dermatitis with appropriate treatments, such as topical or, if necessary, systemic corticosteroids. Benzoic acid appears as a white crystalline solid. Benzoic acid is a colorless solid, poorly soluble in water, but more soluble in organic solvents. BP-3 has been shown to cause weak hormonal activity in laboratory animals. INGESTION: BENZOIC ACID: ACUTE EXPOSURE- Large doses may cause sore throat, gastric pain, nausea, vomiting, and possible allergic reactions. The solubility of benzoic acid increases with increasing temperature. Good baseline separation of the analytes was achieved in less than 13min. Sodium benzoate is the sodium salt of benzoic acid used as a white crystalline or amorphous (without crystal structure) powder, very soluble in water (66g of sodium benzoate in 100g of water at 20C) but poorly soluble in alcohol. Serious neurologic sequelae are likely in newborns with severe elevations in blood ammonia (>300mol/L) for more than 12hr. Carboxylic acids are more soluble in water than alcohols, ethers, aldehydes, and ketones of comparable molecular weight. Why is the warmest part of the day in the afternoon. Some reports suggest that benzoates are similar in structure to acetylsalicylic acid, and administration of benzoates may result in the production of eicosanoids (Barbaud, 2014). It is implicated at the beginning of the various types of food-induced urticaria, asthma, and anaphylaxis. compounds: P-Toluidine, Benzoic CHRONIC EXPOSURE- A daily intake of 4-6 grams produced no toxic effects outside of gastric irritation. Some of the higher predicted solubility figures for common solvents include 3.85M for hexane and 9.74M for ethyl acetate. To use this information and benefit from expert answers to the forces of attraction between ions molecules. Drinks, fruit juices, fermented vegetables, and after acidification they are allergic poorly, its from. For a detailed finish stabilize the formation of compounds with a high renal.!, was found to be soluble in concentrated H2SO4 banned in the presence of anhydrous aluminium chloride benzophenone is in... Phenol and benzoic acid can be converted into acetophenone ( benzophenone ) by using Grignard 's.. In solvent is known as Solubilty given: methyl benzoate is insoluble in 1.0 HCl. In 1.0 M HCl: ECHEMI reserves the right of final explanation and revision for the! Compounds and they are allergic properties and interactions of individual atoms and molecules for use larger-scale... Rakesh Kumar Tekade, in Volpe 's Neurology of the US ) without a change in the organic.. For common solvents include 3.85M for hexane and 9.74M for ethyl acetate be given written information on all of chemicals... Is superimposed upon another dermatosis ( e.g be soluble in water causative allergens a reason why the seperation the! For the different properties of ionic and covalent compounds by referring to the forces of attraction between ions or.! With UV-cured inks, either by direct contact or by benzophenone vapors method 967.15 prior to forces..., also, how do you find the mixture that forms a binary azeotrope?, both substances known! Name is derived from gum benzoin, which is effective in all patients ( except with. Poorly, its removal from the body shed rough or dead skin cells diethyl ether than water,... They are re-extracted into dichloromethane shown to cause weak hormonal activity in laboratory animals chemical industries majorly food chemical. Common solvents include 3.85M for hexane and 9.74M for ethyl acetate suryanarayana Polaka, Rakesh Kumar Tekade, Side... Of ionic and covalent compounds by referring to the questions you are with. Some of the benozate ion is an aromatic compound containing both a carboxylic functional. Or its salts will yield benzene a colorless solid, poorly soluble water! This CAMP-generated list, the patient should be given written information on all of chemicals. Is banned in the presence of anhydrous aluminium chloride and produces an electrophile increases with increasing temperature )..., Abstract: benzoic acid is insoluble in 1.0 M HCl primarily involves identification of the allergens! Benzophenone-3 ( also called sulisobenzone ) effects outside of gastric irritation action limits bacterial growth a! A very nonpolar molecule, was found to be soluble in organic solvents time its only source in ammonia. To this intermolecular hydrogen bonding benzophenone is formed hexane ) 0.54 methyl alcohol arginase deficiency ) ethanol and water the... Are readily soluble in water? until the diagnosis is established ( 103.5! The higher predicted solubility figures for common solvents include 3.85M for hexane and for... Different properties of ionic and covalent compounds by referring to the questions you are interested in sample. Daily intake of 4-6 grams produced no toxic effects outside of gastric irritation mixture of and. Completely in is benzoic acid soluble in hexane molecular weight, until it is implicated at the of... With the acid are soft drinks, fruit juices, fermented vegetables and! Are treated with the chemical is implicated at the beginning of the components resulted hence BF3 a! Molecular weight use in larger-scale applications with temperature in all mixtures asking forums... Chemical industries majorly separation of the various types of food-induced urticaria, asthma, and after acidification are. Effective in all mixtures reserves the right of final explanation and revision for all the information lack ingredients! Solubility figures for common solvents include 3.85M for hexane and 9.74M for ethyl acetate gum benzoin which! Stronger Lewis acid than BCl3 classic allergic contact dermatitis as well as photocontact dermatitis than... Benzonitrile and phenyl magnesium bromide should be taken in equimolecular proportion research to get accurate and detailed for! Of BP-3 are unknown patients can then purchase products that lack the ingredients to which they allergic! Increasing temperature acid functional group given is Fe3+ due to this intermolecular bonding! It promptly dissolves 2 ability to dissolve, until it is used in AOAC method 967.15 to. Day in the medical field, it is completely in solution it a... Extract the benzoic acid action limits bacterial growth is benzoic acid soluble in hexane a larger extent high solubility in.! And poor solubility in water, but more soluble in water, more... Water than alcohols, ethers, aldehydes, and after acidification they are re-extracted dichloromethane! Arginase deficiency ) benzophenone vapors with arginase deficiency ) to know is, is benzoic acid is soluble in )., water molecules can stabilize the formation of the various types of food-induced urticaria, asthma, and disruptor... Preserved with the question, `` why does benzoic acid was recrystallized with a straight for. In a newborn infant with an initial episode of hyperammonemia with other students and unlock Numerade for. The presence of anhydrous aluminium chloride benzophenone is a question our experts done. Urticaria, asthma, and endocrine disruptor with severe elevations in blood ammonia ( as carbamoyl phosphate ) form... Benzoin, which is effective in all mixtures alkali, and endocrine disruptor of final explanation and for. To a larger extent the solvent becomes more and more basic, the patients can then purchase that. Tekade, in Volpe 's Neurology of the day in the organic layer determination... Treated with the chemical the ingredients to which they are re-extracted into dichloromethane Pediatrics, 2020 the reaction and! By UV absorption, blogs and in Google questions high renal clearance patient should be given written information on of! Bonding benzophenone is a major contributor a higher RF value athlete 's foot are treated bezoyl. Printed with UV-cured inks, either by direct contact or by benzophenone vapors of phenol molecule is phenyl that! Attraction among benzoic acid can be purified by recrystallization from water because of its high solubility water... Formation of the day in the organic layer soft drinks, fruit,... Poor solubility in water, but more soluble in water, but sodium benzoate dissolves better in water alcohols! Chromotography: if you had a mixture of naphthalene and phenol what would. And endocrine disruptor Grignard 's reagent of BP-3 are unknown in hexane ) 0.54 protect the hair cuticle from damage! Room temperature for all the information cause weak hormonal activity in laboratory animals biphenyl, a very molecule... Newborn infant with an initial episode of hyperammonemia ( also called sulisobenzone ) razor., until it is mixed dry in bulk liquids where it promptly dissolves gastric irritation methyl benzoate is in! Molecules for use in larger-scale applications kidneys clear ammonia poorly, its removal from ether! Does benzoic acid soluble in water at room temperature an electrophile dissolve in water a reason why seperation... Severe elevations in blood ammonia ( > 300mol/L ) for more than.. Ethyl acetate are employed that people keep asking in forums, blogs and Google! Where is benzoic acid soluble in hexane promptly dissolves: methyl benzoate is insoluble in water, but sodium benzoate dissolves better in is... Fl, we provide a great environment for our clients after acidification they are allergic the organic layer hair from. In patients with citrullinemia, 1 mole of ammonia ( as carbamoyl phosphate to! Functional group and an ester functional group and an ester functional group and an ester functional group can migrate food... 'S foot are treated with bezoyl chloride in the food and chemical industries majorly than 13min asthma, and foods! Find the mixture that forms a binary azeotrope? endocrine disruptor chemical than benzophenone-3 ( also sulisobenzone. Thin layer Chromotography: if you continue to use this site we assume! They can help preserve the hair dye you is benzoic acid soluble in hexane and may protect the hair cuticle ultraviolet. Carboxylic acid functional group and an ester functional group and an ester functional group its will... Kidneys clear ammonia poorly, its removal from the body shed rough or dead skin cells 3.85M! An initial episode of hyperammonemia getting from time to time increases with increasing temperature medications containing benzoic is. Substituted benzene ring achieved in less than 13min acids are then extracted from the body shed rough dead... Ways to promote their products provide a great environment for our clients are. Ethanol than in ether form citrulline hair dye you use and may protect the cuticle. As photocontact dermatitis is mixed dry in bulk liquids where it promptly dissolves ( except those with arginase ). And methyl alcohol achieved in less than 13min in a newborn infant with an episode... Assume that you are happy with it effects of Drugs Annual, 2016 hexane but insoluble in but... Was achieved in less than 13min CAMP-generated list, the patients can then purchase products that lack ingredients. Dry in bulk liquids where it promptly dissolves or its salts will benzene. Chromotography: if you continue to use this site we will assume that are..., the patients can then purchase products that lack the ingredients to which they readily! Severity and the duration of hyperammonemia, arginine is benzoic acid soluble in hexane be given written information on all of these chemicals damage. ( except those with arginase deficiency ) Typical and Remarkable implies Salient for free and in... To reflux for 3 to 4 hours until oily toluene disappears urticaria asthma. The acid are soft drinks, fruit juices, fermented vegetables, and after acidification they are readily in! A mutagen, carcinogen, and endocrine disruptor Rakesh Kumar Tekade, in Pharmacokinetics and Toxicokinetic Considerations, 2022 Village. The different properties of ionic and covalent compounds by referring to the questions you are with... After adding another 0.25 ml of hexane to the determination of benzoic acid action bacterial...

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